On 9 February 2023, a Boeing 777-200ER was en route near Marseille when the cabin crew observed smoke coming from a rear galley oven, which was spreading into the rear passenger cabin. After an initial use of multiple Halon fire extinguishers, the smoke ceased after about 20 minutes, but the fumes remained. Although this meant no ongoing emergency existed, some cabin crew and passengers experienced breathing difficulties and it was decided to return to Amsterdam. The cabin crew response to the situation was subsequently assessed as contrary to applicable procedures and relevant cabin crew training seemingly inadequate.

On 20 February 2021, a Boeing 777-200 climbing through 12,500 feet experienced a sudden right engine failure and fire shortly after thrust had been increased before entering airspace where moderate turbulence was expected. Despite actioning the corresponding drills, the fire did not go out until shortly before landing back at Denver. Engine debris fell to the ground over a wide area, fortuitously with only damage and no injuries. The failure was found to have been initiated by the fatigue failure of a single fan blade after required routine inspections had failed to find early-stage evidence of such a risk.

On 12 July 2013 an unoccupied and unpowered Boeing 787-8, remotely parked at London Heathrow after an arrival earlier the same day caught fire. An investigation found that the source of the fire was an uncontained thermal runaway in the lithium-metal battery within an Emergency Locator Transmitter (ELT). Fifteen Safety Recommendations, all but one to the FAA, were made as a result of the Investigation.

On 7 January 2013, a battery fire on a Japan Air Lines Boeing 787-8 began almost immediately after passengers and crew had left the aircraft after its arrival at Boston on a scheduled passenger flight from Tokyo Narita. The primary structure of the aircraft was undamaged. Investigation found that an internal short circuit within a cell of the APU lithium-ion battery had led to uncontained thermal runaway in the battery leading to the release of smoke and fire. The origin of the malfunction was attributed to system design deficiency and the failure of the type certification process to detect this.

On 26 September 2011, a Boeing 757-200 being operated by United Airlines on a scheduled passenger flight from Chicago to Denver experienced a left engine bird strike during deceleration after landing on runway 35R at destination in normal day visibility. The affected engine ran down as the aircraft cleared the runway and was shut down after a report of smoke being emitted from it. The aircraft was stopped and the remaining engine also shut down prior to a tow to the assigned terminal gate for passenger disembarkation. None of the 185 occupants were injured but the affected engine was severely damaged and there was visible evidence that some debris from it had impacted the aircraft fuselage.