Service providers must balance mission, money, and safety in ways that provide efficient, cost-effective, safe services. They must recognize and observe appropriate boundaries in all these domains to remain viable. Regulators must remain aware of the status of operational safety in the organizations that they oversee, while exercising reasonable and effective controls through a variety of means. In both cases, the cultures of these entities set the tone for their behaviors and performance. One of the most important objectives for regulators is to foster the growth of safety cultures and, therefore, the management capabilities of the service providers that they oversee. This document explores the assessment of regulators’ organizational cultures and their influence on the service provider organizations that they oversee.